Uveal melanoma

A melanoma that originates from uveal MELANOCYTES and is the most common primary intraocular malignancy. Tumors consist of four cell types: epitheloid, intermediate, mixed, and spindle. Somatic mutations in BAP1, GNAQ, GNA11, EIF1AX, and SF3B1 genes have been identified. OMIM: 155720

Also Known As:

Melanoma of the Uvea; Melanoma, Uveal

Neoplasms: 1324753
- Neoplasms by Site: 4
  - Skin Neoplasms: 8909
    - Melanoma: 70723
      - Uveal melanoma: 2393
  - Eye Neoplasms: 61
    - Uveal Neoplasms
      - Uveal melanoma: 2393
- Neoplasms by Histologic Type: 2
  - Germ Cell and Embryonal Neoplasms: 4454
    - Neuroectodermal Tumors: 217
      - Neuroendocrine Tumors: 6270
        Melanoma: 70723
        Uveal melanoma: 2393
  - Nevi and Melanomas: 63
    - Melanoma: 70723
      - Uveal melanoma: 2393
  - Nerve Tissue Neoplasms: 1
    - Neuroectodermal Tumors: 217
      - Neuroendocrine Tumors: 6270
        Melanoma: 70723
        Uveal melanoma: 2393
Skin and Connective Tissue Diseases
- Skin Diseases: 13127
  - Skin Neoplasms: 8909
    - Melanoma: 70723
      - Uveal melanoma: 2393
Eye Diseases: 3522
- Eye Neoplasms: 61
  - Uveal Neoplasms
    - Uveal melanoma: 2393
- Uveal Diseases: 16
  - Uveal Neoplasms
    - Uveal melanoma: 2393

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Disease

Drug/Important Bio-Agent (IBA)